Laura Steenberge's paper on CoQ analogs was posted to bioRxiv.
Andrew Sung and Laura Steenberge successfully defend their Ph.D. theses (on the same day!)
Jonathan Tai successfully defends his Ph.D. thesis
Jonathan Schmitz successfully defends his Ph.D. thesis
Our work describing the structure and function of Aim18 and Aim46, led by Jon Schmitz, was published in JBC.
Vaibhav Deshmukh joins the group as a postdoctoral fellow
Our work describing the structure and function of Aim18 and Aim46, led by Jon Schmitz, was posted on bioRxiv.
Fang accepts a position at Genentech.
Our work describing the structure and functionality of a COQ7:COQ9 complex, led by Mateusz Manicki and Halil Aydin (Frost Lab), was accepted for publication at Molecular Cell.
Mateusz accepts a position at AstraZeneca.
Our work defining an inhibitor of COQ8A, led by Nate Murray, was accepted for publication at Nature Chemical Biology.
Patrick Forny joins the group as a postdoctoral fellow.
Our work defining an allosteric modulator of COQ8A, led by Nate Murray, was published in ACS Chemical Biology.
Nate Murray successfully defends his Ph.D. thesis and accepts a position at Promega in Madison, WI.
Our work defining functions for poorly characterized mitochondrial proteins, led by Jarred Rensvold and Evgenia Shiskova (Coon Lab), was published in Nature.
Our work describing the small molecule modulation of the archetypal UbiB protein COQ8, led by Nate Murray, was posted on bioRxiv.
Our work describing the structure and functionality of a multimeric human COQ7:COQ9 complex, led by Mateusz Manick and by Halil Aydin from Adam Frost's group, was posted on bioRxiv.
Our work describing the structure and function of PREPL, performed in collaboration with Prof. John Creemers' group at KU Leuven, was published in iScience.
Dr. Sean Rogers joins our lab as a postdoctoral fellow after completing his PhD with Prof. Mike Henne at UT Southwestern.
Our manuscript entitled, "UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae," led by Zack Kemmerer and Kyle Robinson, is published in Nature Communications.
Our manuscript entitled, "Defining intermediates and redundancies in coenzyme Q precursor biosynthesis," led by Kyle Robinson, is published in the Journal of Biological Chemistry.
Kyle Robinson successfully defends his PhD entitled, "Defining steps in coenzyme Q cellular distribution and precursor biosynthesis."
Dr. Zixiang Fang joins our lab as a mass spectrometry research specialist after completing his PhD with Saiful Chowdhury at UT Arlington.
Dr. Sanchari Datta joins the lab as a postdoctoral fellow after completing her PhD with Prof. Mike Henne at UT Southwestern.
Zack Kemmerer successfully defends his PhD thesis entitled, "Understanding Atypical Kinases as Essential Factors for the Biosynthesis and Cellular Distribution of Coenzyme Q"
Caroline Fecher joins the lab as a postdoc after completing her PhD with Thomas Misgeld in Munich.
Our laboratory officially reopens in our new location at WashU!
Chelsea White joins the lab as a Lab Manger.
Lab alumna Natalie Niemi begins her independent career as an Assistant Professor of Biochemistry & Molecular Biophysics at WashU.
CMB student Andrew Sung passes his preliminary examination to advance to candidacy.
Our review describing the “systems biochemistry” approach to mitochondrial protein discovery, led by Andrew Sung, was published in Cell Metabolism
Dr. Natalie Niemi has accepted a faculty position to start her own lab at Washington University in St. Louis in the department of Biochemistry and Molecular Biophysics. She will make her official move this summer.
We’re moving! Dave has accepted a position as a BJC Investigator at Washington University School of Medicine in St. Louis starting May 1, 2020. The Pagliarini Lab is scheduled to move this summer.
IPiB student Laura Steenberge passes her preliminary examination to advance to candidacy.
Adam Jochem leaves the lab to begin as a Senior Research Specialist with Dr. Audrey Gasch at the University of Wisconsin-Madison.
IPiB student Abigail Bartlett passes her preliminary examination to advance to candidacy.
Kyle Robinson receives the 2019 Pagliarini Lab Award. This award recognizes Kyle for his tenacity, rigor, and collegiality.
Pagliarini lab is visited by U.S. Senator Tammy Baldwin for a discussion on the lab’s core focus areas and a tour. Learn more about her visit.
Dr. Daniel Pensinger joins the lab as a Postdoctoral Fellow after completing his thesis work with Professor JD Sauer at the University of Wisconsin-Madison.
Undergraduate Alana Caldwell joins the lab as a laboratory assistant.
Jonathan Tai’s F31 predoctoral fellowship proposal entitled “A Yeast Genetics Approach to Identify and Characterize Mitochondrial Transporters in Coenzyme Q Biosynthesis” is funded by the National Institute on Aging.
The Pagliarini lab celebrates its 10 year anniversary.
Our manuscript describing an essential mitochondrial matrix protein phosphatase, led by Natalie Niemi, was published in Nature Communications.
Amy Lin leaves the lab to join Michael Sack’s lab at the National Health Lung Blood Institute, National Institute of Health as a Post baccalaureate Intramural Research Training Award fellow.
Sheila Johnson leaves the lab to pursue her PhD at Harvard University in the Chemical Biology Program.
Sheila Johnson receives her degree in Biochemistry from the University of Wisconsin-Madison
Dave’s R35 proposal entitled “Systems-to-structure approaches for defining mitochondrial protein function” is funded by NIGMS.
IPiB student Jonathan Tai passes his preliminary examination to advance to candidacy.
Zachary Kemmerer is chosen to receive a Denis R.A. and Martha Washburn Wharton Fellowship through the Department of Biochemistry.
Dave is awarded a 2019 H. I. Romnes Faculty Fellowship from the University of Wisconsin-Madison Office for the Vice Chancellor for Research and Graduate Education in recognition of his academic success.
Keith Kamer receives a 2019 Hilldale Undergraduate/Faculty Research Fellowship.
Lainy Von Bank is accepted into the Cellular and Molecular Biology PhD program at the University of Wisconsin-Madison
Sheila Johnson is accepted into the Chemical Biology PhD program at Harvard University.