Pagliarini Lab
Pagliarini Lab
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      • CoQ Biosynthesis
      • Mitochondrial Regulation
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    • Meet Our Team
      • Dave Pagliarini
      • Current Lab
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  • Home
  • Research
    • Overview
    • Systems Biochemistry
    • CoQ Biosynthesis
    • Mitochondrial Regulation
  • Publications
    • Featured
    • All by year
  • News
  • Meet Our Team
    • Dave Pagliarini
    • Current Lab
    • Lab Alumni
  • Contact

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Welcome to the Pagliarini Lab

 We are an interdisciplinary team of scientists driven to understand the biochemical underpinnings of mitochondrial dysfunction in human diseases. Together, we integrate large-scale methodologies with traditional biochemistry to investigate the modulation, adaptation, and basic metabolic function of mitochondria.

Join our team

Recent Discoveries

New enzymes in hydroxy-lipid metabolism

A role for TAGs in mitochondrial stress recovery

A role for TAGs in mitochondrial stress recovery

Rashan et al., NSMB 2025

A role for TAGs in mitochondrial stress recovery

A role for TAGs in mitochondrial stress recovery

A role for TAGs in mitochondrial stress recovery

Baker et al., Nature Cell Biology, 2025

An unexpected role for NDUFAF6 in CI Assembly

A role for TAGs in mitochondrial stress recovery

A new isoprene transporter for CoQ biosynthesis

Sung et al., Nature Metabolism, 2024

A new isoprene transporter for CoQ biosynthesis

A new isoprene transporter for CoQ biosynthesis

A new isoprene transporter for CoQ biosynthesis

Tai et al., Nature Cell Biology, 2023

A novel inhibitor of CoQ biosynthesis

A new isoprene transporter for CoQ biosynthesis

New functions for orphan mitochondrial proteins

Murrary et al., Nature Chem Bio, 2023

New functions for orphan mitochondrial proteins

A new isoprene transporter for CoQ biosynthesis

New functions for orphan mitochondrial proteins

Rensvold et al., Nature 2022

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2025 Pagliarini Lab

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